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Noun Phrase
/ˈrændəmaɪzd kənˈtroʊl: 'traɪəl:/

RDC (Randomised Controlled Trial)

A clinical study where participants are randomly assigned to either an experimental group (receiving the intervention) or a control group (receiving a placebo or standard care).


Purpose: To minimise bias and establish causal relationships between interventions and outcomes.
Gold Standard: Considered the highest quality for testing effectiveness and safety of treatments.

Challenges in Nutrition: Conducting RDCs in nutrition is particularly challenging because it’s hard to control everything people eat over a long time and ensure they follow the diet exactly. In addition, individual differences in metabolism, lifestyle, and genetics can affect results, making it tricky to isolate the impact of a single food or nutrient.